Glyburide/metformin (Glucovance), rosiglitazone/metformin (Avandamet), glipizide/metformin (Metaglip), and pioglitazone/metformin (Actoplus met) are four relatively new combination pills that are on the market to treat diabetes.
Glucovance combines glyburide with metformin in varying doses.
Avandamet is a combination of varying doses of Avandia and metformin.
Actoplusmet is a combination of varying doses of pioglitazone and metformin.
Metaglip is a combination pill containing glipizide and metformin in varying strengths.
The benefit to these combination drugs is that there are fewer pills to take, hopefully leading to better compliance. While they work well, I personally like to give patients individual medications until I know what doses are working, and then switch to a combination pill once the patient has been stable on the doses of individual medications for a period of time.
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